Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.31 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.30 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.30 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | LDHA | P00338 | 1/20 | 0.30 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.30 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8530828 | 0.74 | FFAR3 (0.40) | FFAR3EGLN1ALDH1A1HCAR2HDAC3 | |
| SCHEMBL1640177 | 0.65 | — | — | |
| SCHEMBL1181781 | 0.61 | FFAR3 (0.44) | FFAR3TSHREGLN1ALDH1A1HDAC3 | |
| Glycolic Acid SCHEMBL3826792 | 0.60 | — | — | |
| Succinic Acid SCHEMBL2804358 | 0.60 | EGLN1 (0.69) | FFAR3TSHREGLN1ALDH1A1HDAC3 | |
| Propionic Acid SCHEMBL36645 | 0.60 | — | — | |
| Malonic Acid SCHEMBL2412964 | 0.60 | LDHA (0.69) | FFAR3TSHREGLN1ALDH1A1HCAR2 | |
| Malonic Acid SCHEMBL2509322 | 0.60 | LDHA (0.69) | FFAR3TSHREGLN1ALDH1A1HCAR2 | |
| SCHEMBL25218427 | 0.59 | FFAR3 (0.42) | FFAR3TSHREGLN1ALDH1A1HDAC3 | |
| Chloroacetic Acid SCHEMBL9267847 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1050534-B1 | 2,3-methano-amino acid derivatives, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2001-12-05 | — | — | EP | disclosed |
| EP-1050534-A1 | 2,3-methano-amino acid derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 2000-11-08 | — | — | EP | disclosed |