Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 6/20 | 0.69 |
| ▸ | LMNA | P02545 | 4/20 | 0.69 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.69 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.69 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.59 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 4/20 | 0.52 |
| ▸ | PHF8 | Q9UPP1 | 5/20 | 0.50 |
| ▸ | KDM2A | Q9Y2K7 | 5/20 | 0.50 |
| ▸ | KDM5C | P41229 | 4/20 | 0.50 |
| ▸ | KDM6B | O15054 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.50 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Levulinic Acid SCHEMBL12981251 | 0.87 | LMNA (0.82) | EGLN1LMNAALKBH5SUCNR1SLC15A2 | |
| Adipic Acid SCHEMBL12980634 | 0.86 | LMNA (0.73) | LMNATSHRALDH1A1SLC22A6OR51E2 | |
| Glutarate SCHEMBL29217352 | 0.86 | SLC22A6 (0.73) | LMNATSHRALDH1A1SLC22A6OR51E2 | |
| Succinic Acid SCHEMBL3628497 | 0.84 | EGLN1 (0.82) | EGLN1LMNAALKBH5SUCNR1SLC15A2 | |
| Succinic Acid SCHEMBL30575212 | 0.84 | EGLN1 (0.82) | EGLN1LMNAALKBH5SUCNR1SLC15A2 | |
| Succinic Acid SCHEMBL27584447 | 0.84 | EGLN1 (0.82) | EGLN1LMNAALKBH5SUCNR1SLC15A2 | |
| Succinic Acid SCHEMBL24696 | 0.83 | LMNA (1.00) | EGLN1LMNAALKBH5SUCNR1SLC15A2 | |
| Succinic Acid SCHEMBL21867134 | 0.83 | LMNA (1.00) | EGLN1LMNAALKBH5SUCNR1SLC15A2 | |
| Succinic Acid SCHEMBL1331200 | 0.83 | — | — | |
| Succinic Acid SCHEMBL4269130 | 0.83 | LMNA (1.00) | EGLN1LMNAALKBH5SUCNR1SLC15A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114262424-B | Preparation method of epoxy solder resist acrylic oligomer with high sensitivity and photoresist or ink composition | 广州斯达利电子原料有限公司 | 2024-05-24 | — | — | CN | claimed |
| CN-117887303-A | Preparation method of epoxy solder resist acrylic oligomer with high sensitivity and photoresist or ink composition | 广州斯达利电子原料有限公司 | 2024-04-16 | — | — | CN | claimed |
| CN-1724625-A | Water-base detergent composite for removing burning residual and manufacturing method | KAM BIOTECH ASIAN CO LTD (KR) | 2006-01-25 | — | — | CN | claimed |
| CN-114262424-B | Preparation method of epoxy solder resist acrylic oligomer with high sensitivity and photoresist or ink composition | 广州斯达利电子原料有限公司 | 2024-05-24 | — | — | CN | disclosed |
| CN-117887303-A | Preparation method of epoxy solder resist acrylic oligomer with high sensitivity and photoresist or ink composition | 广州斯达利电子原料有限公司 | 2024-04-16 | — | — | CN | disclosed |
| CN-107298761-B | A kind of preparation method of vitamin E polyethylene glycol monomethyl ether succinate | 浙江信桥生化科技有限公司 | 2019-09-20 | — | — | CN | disclosed |
| CN-107298761-A | A kind of preparation method of vitamin E polyethylene glycol monomethyl ether succinate | 浙江信桥生化科技有限公司 | 2017-10-27 | — | — | CN | disclosed |
| US-8440641-B2 | Phthalocyanine salt formulations | CASE WESTERN RESERVE UNIVERSITY (US) | 2013-05-14 | — | — | US | disclosed |
| US-20120258249-A1 | LOW/ZERO VOC GLYCOL ETHER-ESTERS AS COALESCENTS FOR AQUEOUS POLYMERIC DISPERSIONS | ADAMSON LINDA A (US) | 2012-10-11 | — | — | US | disclosed |
| WO-2010108056-A1 | PHTHALOCYANINE SALT FORMULATIONS | CASE WESTERN RESERVE UNIVERSITY (US) | 2010-09-23 | — | — | WO | disclosed |
| US-20100240609-A1 | PHTHALOCYANINE SALT FORMULATIONS | CASE WESTERN RESERVE UNIVERSITY (US) | 2010-09-23 | — | — | US | disclosed |
| CN-1724625-A | Water-base detergent composite for removing burning residual and manufacturing method | KAM BIOTECH ASIAN CO LTD (KR) | 2006-01-25 | — | — | CN | disclosed |
| US-4740450-A | COATING WITH PHOTOSENSITIVE LAYER CONTAINING SCRATCH IMPROVER; DRYING, MIGRATION | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 1988-04-26 | — | — | US | disclosed |
| US-4699859-A | CONTAINING PHENOL WHICH PREVENTS CURING OF CERTAIN SEGMENTS | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 1987-10-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120258249-A1 | LOW/ZERO VOC GLYCOL ETHER-ESTERS AS COALESCENTS FOR AQUEOUS POLYMERIC DISPERSIONS | HDLBP, COG7, COG4 | EGLN1 1155/4885LMNA 1937/4885ALKBH5 567/4885 |
| US-20100240609-A1 | PHTHALOCYANINE SALT FORMULATIONS | PHLPP1, PHLPP2, CRY1 | EGLN1 2319/4885LMNA 3827/4885ALKBH5 4177/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.