Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 4/20 | 0.44 |
| ▸ | CTSS | P25774 | 2/20 | 0.44 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.38 |
| ▸ | AKT1 | P31749 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7307182 | 1.00 | CTSK (0.44) | CTSKCTSSKLK5MEN1KMT2A | |
| SCHEMBL7353047 | 0.89 | CTSK (0.45) | CTSKCTSSKLK5MEN1KMT2A | |
| SCHEMBL8086793 | 0.87 | KMT2A (0.52) | CTSKCTSSMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8075350 | 0.87 | KMT2A (0.52) | CTSKCTSSMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8083658 | 0.86 | CTSK (0.46) | CTSKCTSSMEN1KMT2AS1PR3 | |
| SCHEMBL7314443 | 0.82 | CTSK (0.48) | CTSKCTSSKLK5ATMAPP | |
| SCHEMBL7313867 | 0.82 | CTSK (0.48) | CTSKCTSSKLK5ATMAPP | |
| SCHEMBL7306604 | 0.81 | MAPT (0.46) | CTSKCTSSMEN1KMT2AALDH1A1 | |
| SCHEMBL9229477 | 0.80 | AKT1 (0.38) | CTSKCTSSKLK5MEN1KMT2A | |
| SCHEMBL9331274 | 0.80 | CTSK (0.53) | CTSKCTSSMEN1KMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1041064-A2 | N-substituted alpha aminoacid amides as calcium channel modulators | ELI LILLY AND COMPANY LIMITED (GB) | 2000-10-04 | — | — | EP | disclosed |
| EP-0805147-A1 | Novel N-substituted alpha aminoacid amides as calcium channel modulators | LILLY INDUSTRIES LIMITED (GB) | 1997-11-05 | — | — | EP | disclosed |