Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 5/20 | 0.48 |
| ▸ | CTSS | P25774 | 5/20 | 0.48 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.40 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7314443 | 1.00 | CTSK (0.48) | CTSKCTSSCXCR3APPCTSL | |
| SCHEMBL7313561 | 0.87 | CTSK (0.47) | CTSKCTSSCXCR3CTSLCTSB | |
| SCHEMBL7309512 | 0.83 | CA12 (0.50) | CTSKCTSSCTSLCTSBKLK5 | |
| SCHEMBL7301520 | 0.82 | CTSK (0.44) | CTSKCTSSCXCR3CTSLCTSB | |
| SCHEMBL8613638 | 0.82 | CA2 (0.52) | CTSKCTSSCTSLCTSBKLK5 | |
| SCHEMBL7307182 | 0.82 | CTSK (0.44) | CTSKCTSSAPPKLK5ATM | |
| SCHEMBL7353047 | 0.82 | CTSK (0.45) | CTSKCTSSKLK5 | |
| SCHEMBL7304711 | 0.82 | CTSK (0.44) | CTSKCTSSAPPKLK5ATM | |
| SCHEMBL9229164 | 0.79 | SDCBP (0.48) | CTSKCTSS | |
| SCHEMBL7834971 | 0.79 | CTSK (0.55) | CTSKCTSSCXCR3CTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1041064-A2 | N-substituted alpha aminoacid amides as calcium channel modulators | ELI LILLY AND COMPANY LIMITED (GB) | 2000-10-04 | — | — | EP | disclosed |
| EP-0805147-A1 | Novel N-substituted alpha aminoacid amides as calcium channel modulators | LILLY INDUSTRIES LIMITED (GB) | 1997-11-05 | — | — | EP | disclosed |