Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 5/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 3/20 | 0.36 |
| ▸ | KDR | P35968 | 2/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | TNK1 | Q13470 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7298324 | 0.86 | ALK (0.45) | ALKIRAK4ABCB1FFAR4MGLL | |
| SCHEMBL7297025 | 0.86 | KMT2A (0.41) | IRAK4ABCB1GPR119AR | |
| SCHEMBL7306131 | 0.83 | ITGB3 (0.39) | ALKHRH3GPR119 | |
| SCHEMBL7293154 | 0.83 | ALDH1A1 (0.34) | ALKHRH3GPR119 | |
| SCHEMBL7306124 | 0.83 | ITGB3 (0.39) | ALKHRH3GPR119 | |
| SCHEMBL7306203 | 0.80 | AR (0.39) | ALKIRAK4KDRHRH3GPR119 | |
| SCHEMBL7306198 | 0.80 | AR (0.39) | ALKIRAK4KDRHRH3GPR119 | |
| SCHEMBL7304758 | 0.77 | PANK3 (0.39) | IRAK4HRH3GPR119AR | |
| SCHEMBL7303451 | 0.76 | GPR119 (0.42) | IRAK4HRH3GPR119AR | |
| SCHEMBL356713 | 0.74 | GPR119 (0.54) | IRAK4GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0537980-A1 | Cyclohexaneacetic acid derivatives as inhibitors of fibrinogen-dependent blood platelet aggregation | GLAXO GROUP LIMITED (GB) | 1993-04-21 | — | — | EP | disclosed |