SCHEMBL7304840

SCHEMBL7304840

CCCN1CCN(CCCCN2C(=O)OC(N3CCN(CC(=O)O)CC3)C2C)CC1

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 1/20 0.33
S1PR1 P21453 1/20 0.33
TP53 P04637 1/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
KCNH2 Q12809 1/20 0.31
RECQL P46063 1/20 0.31
ALDH1A1 P00352 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7313581 0.91 ALDH1A1 (0.33) S1PR1SMN1; SMN2RECQLALDH1A1
SCHEMBL7307068 0.91 CYP1A2 (0.38) HRH3SMN1; SMN2KCNH2
SCHEMBL7311142 0.91 GLA (0.34) HRH3SMN1; SMN2KCNH2
SCHEMBL7317112 0.89 OPRL1 (0.38) TP53ALDH1A1
SCHEMBL7316047 0.87 GRIN1 (0.42)
SCHEMBL7300811 0.86 MAOB (0.37)
SCHEMBL7315052 0.85 ALDH1A1 (0.44) SMN1; SMN2ALDH1A1
SCHEMBL7309061 0.85 HSD17B10 (0.35) SMN1; SMN2RECQLALDH1A1HSD17B10
SCHEMBL7307179 0.84 OPRL1 (0.33) SMN1; SMN2
SCHEMBL7313049 0.84 SMN1; SMN2 (0.38) TP53SMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0711770-A1 Antagonists of adhesion receptors MERCK PATENT GmbH (DE) 1996-05-15 EP disclosed