Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 8/20 | 0.32 |
| ▸ | PTGER3 | P43115 | 7/20 | 0.32 |
| ▸ | PTGER2 | P43116 | 6/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HRH2 | P25021 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | DRD5 | P21918 | 1/20 | 0.30 |
| ▸ | HTR7 | P34969 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7307068 | 0.95 | CYP1A2 (0.38) | HRH3PTGER4PTGER3PTGER2SMN1; SMN2 | |
| SCHEMBL7308037 | 0.91 | PKM (0.35) | GLASMN1; SMN2CYP1A2MAPK1 | |
| SCHEMBL7304840 | 0.91 | HRH3 (0.33) | HRH3SMN1; SMN2KCNH2 | |
| SCHEMBL7313049 | 0.88 | SMN1; SMN2 (0.38) | SMN1; SMN2HRH2HRH1PAOXDRD2 | |
| SCHEMBL7317126 | 0.87 | GRIN1 (0.42) | HTR7 | |
| SCHEMBL7304525 | 0.86 | CYP1A2 (0.38) | PTGER4PTGER3PTGER2SMN1; SMN2CYP1A2 | |
| SCHEMBL7307179 | 0.86 | OPRL1 (0.33) | GLASMN1; SMN2HRH2HRH1PAOX | |
| SCHEMBL7311515 | 0.86 | MAOB (0.37) | GLASMN1; SMN2CYP1A2MAPK1 | |
| SCHEMBL7311744 | 0.85 | HTR7 (0.43) | HTR1ADRD2HTR7DRD3 | |
| SCHEMBL7308005 | 0.85 | GLA (0.39) | GLACYP1A2PAOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711770-A1 | Antagonists of adhesion receptors | MERCK PATENT GmbH (DE) | 1996-05-15 | — | — | EP | disclosed |