Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | FPR2 | P25090 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.30 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7304525 | 0.91 | CYP1A2 (0.38) | ALDH1A1KMT2AKDM4EMEN1SMN1; SMN2 | |
| SCHEMBL7304840 | 0.91 | HRH3 (0.33) | ALDH1A1RECQLSMN1; SMN2S1PR1 | |
| SCHEMBL7308037 | 0.91 | PKM (0.35) | ALDH1A1KMT2AKDM4EMEN1SMN1; SMN2 | |
| SCHEMBL7310453 | 0.89 | OPRL1 (0.34) | ALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL7300811 | 0.88 | MAOB (0.37) | — | |
| SCHEMBL7309302 | 0.85 | ALDH1A1 (0.44) | ALDH1A1KMT2AMEN1RECQLSMN1; SMN2 | |
| SCHEMBL7316047 | 0.85 | GRIN1 (0.42) | — | |
| SCHEMBL7309061 | 0.85 | HSD17B10 (0.35) | ALDH1A1KMT2AKDM4EMEN1CYP2D6 | |
| SCHEMBL7317073 | 0.84 | MEN1 (0.33) | ALDH1A1KMT2AMEN1SMN1; SMN2FPR2 | |
| SCHEMBL7314712 | 0.84 | SMN1; SMN2 (0.38) | ALDH1A1KMT2AKDM4EMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711770-A1 | Antagonists of adhesion receptors | MERCK PATENT GmbH (DE) | 1996-05-15 | — | — | EP | disclosed |