Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.37 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 2/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7314586 | 0.92 | MAOB (0.37) | MAOBDAOHTR4 | |
| SCHEMBL7311515 | 0.92 | MAOB (0.37) | MAOBDAOHTR4 | |
| SCHEMBL7313581 | 0.88 | ALDH1A1 (0.33) | — | |
| SCHEMBL7304840 | 0.86 | HRH3 (0.33) | — | |
| SCHEMBL7304254 | 0.85 | HRH3 (0.33) | — | |
| SCHEMBL7313310 | 0.85 | MAOB (0.35) | MAOBDAOSIGMAR1HTR4 | |
| SCHEMBL7306138 | 0.85 | SMN1; SMN2 (0.36) | MAOBDAOSIGMAR1HTR4 | |
| SCHEMBL7309302 | 0.82 | ALDH1A1 (0.44) | SIGMAR1 | |
| SCHEMBL7316047 | 0.82 | GRIN1 (0.42) | SIGMAR1 | |
| SCHEMBL7309061 | 0.82 | HSD17B10 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711770-A1 | Antagonists of adhesion receptors | MERCK PATENT GmbH (DE) | 1996-05-15 | — | — | EP | disclosed |