Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 16/20 | 0.80 |
| ▸ | ITGA2B | P08514 | 16/20 | 0.80 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7297075 | 0.89 | ITGB3 (1.00) | ITGB3ITGA2B | |
| SCHEMBL7298754 | 0.83 | ITGB3 (0.71) | ITGB3ITGA2B | |
| SCHEMBL7306246 | 0.82 | ITGB3 (0.77) | ITGB3ITGA2B | |
| SCHEMBL9223584 | 0.77 | ITGB3 (0.80) | ITGB3ITGA2B | |
| SCHEMBL8649066 | 0.73 | ITGB3 (0.60) | ITGB3ITGA2BKDM4EHTTSMN1; SMN2 | |
| SCHEMBL8881759 | 0.72 | SMN1; SMN2 (0.55) | ITGB3ITGA2BSMN1; SMN2KCNH2 | |
| SCHEMBL7302505 | 0.70 | ITGB3 (0.69) | ITGB3ITGA2BKDM4EHTT | |
| SCHEMBL7363765 | 0.69 | ITGB3 (0.73) | ITGB3ITGA2B | |
| SCHEMBL8648281 | 0.69 | SMN1; SMN2 (0.60) | HTTSMN1; SMN2 | |
| SCHEMBL17994013 | 0.69 | KDM4E (0.63) | ITGB3ITGA2BKDM4EHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0445796-B1 | Derivatives of acetic acid containing peptide bonds | HOFFMANN LA ROCHE (CH) | 1998-06-17 | — | — | EP | disclosed |
| EP-0445796-A2 | Derivatives of acetic acid | F. HOFFMANN-LA ROCHE AG (CH) | 1991-09-11 | — | — | EP | disclosed |