Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.46 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | CCR3 | P51677 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.42 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9562508 | 0.81 | MEN1 (0.44) | CHRM2CHRM4CHRM5CHRM1DRD2 | |
| SCHEMBL9561894 | 0.81 | BCHE (0.50) | CHRM2CHRM4CHRM5CHRM1DRD2 | |
| SCHEMBL8540534 | 0.81 | CARM1 (0.43) | BCHECCR3MEN1KMT2ACARM1 | |
| SCHEMBL8549348 | 0.80 | GRIN2B (0.53) | CHRM2CHRM4CHRM5CHRM1DRD2 | |
| SCHEMBL466863 | 0.80 | GRIN2B (0.61) | CHRM2CHRM4CHRM5CHRM1DRD2 | |
| SCHEMBL20548523 | 0.76 | GRIN2B (0.67) | GRIN2B | |
| SCHEMBL8543860 | 0.76 | LMNA (0.37) | CCR3MEN1KMT2AGRIN2B | |
| SCHEMBL9562536 | 0.75 | KCNH2 (0.48) | ACHEBCHECCR3MEN1KMT2A | |
| SCHEMBL9562478 | 0.74 | GRIN2B (0.60) | DRD2ACHEBCHEMEN1KMT2A | |
| SCHEMBL8547677 | 0.74 | CARM1 (0.47) | CHRM2CHRM4CHRM5CHRM1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0481853-A1 | 1-(3,4-Dihydro-2-oxo-1H-quinoline-6-yl)-2-[4-(2-phenylethyl)-piperidin-1-yl]ethanol and -ethane, their preparation and their use in therapeutics | SYNTHELABO (FR) | 1992-04-22 | — | — | EP | disclosed |