Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 1/20 | 0.43 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.43 |
| ▸ | CCR3 | P51677 | 7/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | OGT | O15294 | 1/20 | 0.37 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8547677 | 0.92 | CARM1 (0.47) | CARM1PRMT6CCR3MEN1KMT2A | |
| SCHEMBL8547391 | 0.84 | CARM1 (0.39) | CARM1PRMT6MEN1KMT2AGRIN2B | |
| SCHEMBL8548066 | 0.84 | CARM1 (0.39) | CARM1PRMT6MEN1KMT2AGRIN2B | |
| SCHEMBL8547879 | 0.84 | CARM1 (0.39) | CARM1PRMT6MEN1KMT2AGRIN2B | |
| SCHEMBL8549348 | 0.83 | GRIN2B (0.53) | CARM1PRMT6CCR3MEN1KMT2A | |
| SCHEMBL8543860 | 0.82 | LMNA (0.37) | CCR3MEN1KMT2AGRIN2BOGT | |
| SCHEMBL8544708 | 0.82 | GRIN2B (0.45) | CARM1PRMT6CCR3MEN1KMT2A | |
| SCHEMBL8545326 | 0.82 | GRIN2B (0.45) | CARM1PRMT6CCR3MEN1KMT2A | |
| SCHEMBL8545330 | 0.82 | GRIN2B (0.45) | CARM1PRMT6CCR3MEN1KMT2A | |
| SCHEMBL7305064 | 0.81 | CHRM2 (0.46) | CARM1PRMT6CCR3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709384-A1 | Benzylpiperidine derivatives having high affinity for binding sites of aminoacid receptors | MERCK PATENT GmbH (DE) | 1996-05-01 | — | — | EP | claimed |
| EP-0709384-B1 | Benzylpiperidine derivatives having high affinity for binding sites of aminoacid receptors | MERCK PATENT GMBH (DE) | 1998-12-23 | — | — | EP | disclosed |
| EP-0709384-A1 | Benzylpiperidine derivatives having high affinity for binding sites of aminoacid receptors | MERCK PATENT GmbH (DE) | 1996-05-01 | — | — | EP | disclosed |