Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SCN4A | P35499 | 2/20 | 0.39 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL963521 | 0.87 | CA4 (0.41) | TAAR1HTR2ALTA4HSLC6A4 | |
| Hydrochloric Acid SCHEMBL29278092 | 0.85 | CA4 (0.39) | TAAR1HTR2ASLC6A4 | |
| SCHEMBL29138031 | 0.83 | LTA4H (0.38) | TAAR1HTR2ALTA4HSLC6A4 | |
| SCHEMBL11515377 | 0.80 | TAAR1 (0.44) | TAAR1HTR2ALTA4HTSHRSCN4A | |
| SCHEMBL29138026 | 0.79 | SLC6A4 (0.41) | TAAR1TSHRSLC6A4 | |
| SCHEMBL30309249 | 0.78 | HRH1 (0.52) | TAAR1HTR2ALTA4HPLA2G2ASLC6A4 | |
| SCHEMBL17459935 | 0.76 | TAAR1 (0.41) | TAAR1HTR2ALTA4HSCN4APLA2G2A | |
| SCHEMBL6482154 | 0.76 | TAAR1 (0.41) | TAAR1HTR2ALTA4HTSHRSCN4A | |
| SCHEMBL3160069 | 0.76 | MTNR1A (0.50) | TAAR1HTR2ALTA4HSLC6A4 | |
| SCHEMBL8694787 | 0.76 | LMNA (0.42) | TAAR1HTR2ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0931788-B1 | Metalloprotease inhibitors | PFIZER LTD (GB) | 2002-11-06 | — | — | EP | disclosed |
| US-6090852-A | MATRIX METALLOPROTEASE INHIBITOR | PFIZER INC (US) | 2000-07-18 | — | — | US | disclosed |
| EP-0931788-A2 | Metalloprotease inhibitors | Pfizer Limited (GB) | 1999-07-28 | — | — | EP | disclosed |
| EP-0226475-A1 | Diphenoxyethyl amine derivatives, process for their preparation and pharmaceutical compositions containing them | Albert ROLLAND S.A. Société dite (FR) | 1987-06-24 | — | — | EP | disclosed |
| EP-0226475-A1 | Diphenoxyethyl amine derivatives, process for their preparation and pharmaceutical compositions containing them | Albert ROLLAND S.A. Société dite (FR) | 1987-06-24 | — | — | EP | disclosed |
| EP-0226475-A1 | Diphenoxyethyl amine derivatives, process for their preparation and pharmaceutical compositions containing them | Albert ROLLAND S.A. Société dite (FR) | 1987-06-24 | — | — | EP | disclosed |