SCHEMBL6482154

SCHEMBL6482154

NCC(Cl)Oc1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 4/20 0.41
HTR2A P28223 1/20 0.41
MTNR1A P48039 1/20 0.38
MTNR1B P49286 1/20 0.38
SCN4A P35499 2/20 0.36
LTA4H P09960 2/20 0.36
PLA2G2A P14555 1/20 0.36
AOC3 Q16853 1/20 0.36
DPP4 P27487 1/20 0.36
TSHR P16473 1/20 0.36
KCNA3 P22001 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11802140 0.79 MTNR1A (0.39) TAAR1MTNR1AMTNR1BSCN4ALTA4H
SCHEMBL28057724 0.77 MTNR1A (0.38) MTNR1AMTNR1BLTA4HTSHRKCNA3
SCHEMBL8108204 0.77 MTNR1A (0.42) MTNR1AMTNR1BLTA4HTSHRKCNA3
SCHEMBL11515377 0.76 TAAR1 (0.44) TAAR1HTR2ASCN4ALTA4HPLA2G2A
SCHEMBL7305170 0.76 TAAR1 (0.44) TAAR1HTR2ASCN4ALTA4HPLA2G2A
SCHEMBL15349936 0.76 LMNA (0.50) TAAR1MTNR1AMTNR1BSCN4AKCNA3
SCHEMBL10372698 0.74 SLC6A4 (0.41) MTNR1AMTNR1BLTA4H
SCHEMBL11072413 0.73 TSHR (0.41) TAAR1SCN4ALTA4HDPP4TSHR
SCHEMBL17459935 0.73 TAAR1 (0.41) TAAR1HTR2ASCN4ALTA4HPLA2G2A
SCHEMBL3160069 0.73 MTNR1A (0.50) TAAR1HTR2AMTNR1AMTNR1BLTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030055066-A1 Phenoxypropanol connected with phenylpiperazine and phenoxyalkylamine terminal in its side chain LIN, TONG-HO (TW) 2003-03-20 US claimed
US-6846826-B2 Phenoxypropanol connected with phenylpiperazine and phenoxyalkylamine terminal in its side chain Chen, Ing-Jun (TW) 2005-01-25 US disclosed
US-20030055066-A1 Phenoxypropanol connected with phenylpiperazine and phenoxyalkylamine terminal in its side chain LIN, TONG-HO (TW) 2003-03-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030055066-A1 Phenoxypropanol connected with phenylpiperazine and phenoxyalkylamine terminal in its side chain KCNH2, ADRB3, KCNH3 TAAR1 506/4885HTR2A 365/4885MTNR1A 833/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.