Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LAP3 | P28838 | 4/20 | 0.62 |
| ▸ | ANPEP | P15144 | 2/20 | 0.62 |
| ▸ | RNPEP | Q9H4A4 | 2/20 | 0.62 |
| ▸ | DNPEP | Q9ULA0 | 2/20 | 0.62 |
| ▸ | MMP8 | P22894 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.48 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CTSS | P25774 | 2/20 | 0.48 |
| ▸ | CTSL | P07711 | 1/20 | 0.48 |
| ▸ | CTSB | P07858 | 1/20 | 0.48 |
| ▸ | CTSK | P43235 | 1/20 | 0.48 |
| ▸ | NMBR | P28336 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16254383 | 0.81 | LAP3 (0.63) | LAP3ANPEPRNPEPDNPEPL3MBTL1 | |
| SCHEMBL17624753 | 0.81 | MME (0.67) | — | |
| SCHEMBL18435373 | 0.80 | LAP3 (0.61) | LAP3ANPEPRNPEPDNPEPL3MBTL1 | |
| SCHEMBL19289912 | 0.80 | LAP3 (0.61) | LAP3ANPEPRNPEPDNPEPL3MBTL1 | |
| SCHEMBL7306277 | 0.80 | ANPEP (0.64) | ANPEPMMP8MEN1KMT2A | |
| SCHEMBL7306287 | 0.80 | ANPEP (0.64) | ANPEPMMP8MEN1KMT2A | |
| SCHEMBL7299696 | 0.80 | CAPN1 (0.56) | ANPEPDNPEPMMP8CTSLCTSB | |
| SCHEMBL7304649 | 0.80 | CAPN1 (0.56) | ANPEPDNPEPMMP8CTSLCTSB | |
| SCHEMBL7299705 | 0.80 | CAPN1 (0.56) | ANPEPDNPEPMMP8CTSLCTSB | |
| SCHEMBL7304634 | 0.80 | CAPN1 (0.56) | ANPEPDNPEPMMP8CTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5214056-A | Thiol protease inhibitors | JAPAN TOBACCO INC. (JP) | 1993-05-25 | — | — | US | claimed |
| US-5214056-A | Thiol protease inhibitors | JAPAN TOBACCO INC. (JP) | 1993-05-25 | — | — | US | disclosed |
| EP-0460239-A1 | 1,3,2-DIOXATHIOLANE OXIDE DERIVATIVE | Japan Tobacco Inc. (JP) | 1991-12-11 | — | — | EP | disclosed |