Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPA1 | P15085 | 2/20 | 0.45 |
| ▸ | CPA2 | P48052 | 2/20 | 0.45 |
| ▸ | CPA4 | Q9UI42 | 2/20 | 0.45 |
| ▸ | MME | P08473 | 2/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP3 | P08254 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | ERAP2 | Q6P179 | 3/20 | 0.42 |
| ▸ | ERAP1 | Q9NZ08 | 3/20 | 0.42 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | IL1RN | P18510 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7315045 | 1.00 | CPA1 (0.45) | CPA1CPA2CPA4MMEMMP2 | |
| SCHEMBL7315037 | 1.00 | CPA1 (0.45) | CPA1CPA2CPA4MMEMMP2 | |
| SCHEMBL7309259 | 0.92 | CTSL (0.46) | CPA1CPA2CPA4MMEMMP2 | |
| SCHEMBL7309270 | 0.92 | CTSL (0.46) | CPA1CPA2CPA4MMEMMP2 | |
| SCHEMBL7329474 | 0.92 | CTSL (0.46) | CPA1CPA2CPA4MMEMMP2 | |
| SCHEMBL7310567 | 0.89 | MMP1 (0.45) | MMP3CTSL | |
| SCHEMBL7314942 | 0.89 | MMP1 (0.45) | MMP3CTSL | |
| SCHEMBL7314951 | 0.89 | MMP1 (0.45) | MMP3CTSL | |
| SCHEMBL7401297 | 0.84 | SMN1; SMN2 (0.44) | MMELNPEPSMN1; SMN2GAA | |
| SCHEMBL7317922 | 0.83 | MMP1 (0.47) | MMP3CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5380921-A | Enzyme inhibitors for endothelin converting enzyme for cardiovascular disorders and atherosclerosis | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1995-01-10 | — | — | US | disclosed |
| EP-0623625-A1 | Aminophosphonic acid derivative | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1994-11-09 | — | — | EP | disclosed |