Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 2/20 | 0.45 |
| ▸ | MMP3 | P08254 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CTSL | P07711 | 4/20 | 0.45 |
| ▸ | CTSK | P43235 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7314942 | 1.00 | MMP1 (0.45) | MMP1MMP3MEN1KMT2ACTSL | |
| SCHEMBL7314951 | 1.00 | MMP1 (0.45) | MMP1MMP3MEN1KMT2ACTSL | |
| SCHEMBL7317922 | 0.95 | MMP1 (0.47) | MMP1MMP3MEN1KMT2ACTSL | |
| SCHEMBL7315045 | 0.89 | CPA1 (0.45) | MMP3CTSL | |
| SCHEMBL7315037 | 0.89 | CPA1 (0.45) | MMP3CTSL | |
| SCHEMBL7305566 | 0.89 | CPA1 (0.45) | MMP3CTSL | |
| SCHEMBL7309270 | 0.85 | CTSL (0.46) | MMP1MMP3MEN1KMT2ACTSL | |
| SCHEMBL7329474 | 0.85 | CTSL (0.46) | MMP1MMP3MEN1KMT2ACTSL | |
| SCHEMBL7309259 | 0.85 | CTSL (0.46) | MMP1MMP3MEN1KMT2ACTSL | |
| SCHEMBL7305651 | 0.82 | MMP3 (0.52) | MMP1MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5380921-A | Enzyme inhibitors for endothelin converting enzyme for cardiovascular disorders and atherosclerosis | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1995-01-10 | — | — | US | disclosed |
| EP-0623625-A1 | Aminophosphonic acid derivative | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1994-11-09 | — | — | EP | disclosed |