Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10159595 | 0.81 | HIF1A (0.55) | HIF1AHSD11B1NPC1POLBRAB9A | |
| Hydrochloric Acid SCHEMBL9554062 | 0.80 | KDM4E (0.59) | HIF1AHSD11B1POLBALDH1A1KDM4E | |
| SCHEMBL27373120 | 0.80 | SMN1; SMN2 (0.53) | HIF1AALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL2755865 | 0.79 | KDM4E (0.62) | HIF1AHSD11B1NPC1POLBRAB9A | |
| SCHEMBL12999538 | 0.78 | SMN1; SMN2 (0.61) | POLBRAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL7303820 | 0.76 | OPRM1 (0.50) | HIF1AHSD11B1NPC1POLBRAB9A | |
| SCHEMBL424285 | 0.76 | HIF1A (0.59) | HIF1AHSD11B1NPC1POLBRAB9A | |
| SCHEMBL11613463 | 0.76 | HIF1A (0.53) | HIF1AHSD11B1NPC1POLBRAB9A | |
| SCHEMBL11610587 | 0.75 | RAB9A (0.56) | HSD11B1NPC1RAB9AALDH1A1MEN1 | |
| SCHEMBL31298063 | 0.75 | MEN1 (0.67) | HIF1AHSD11B1NPC1POLBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0410260-A2 | Peptidyl aminodiol renin inhibitors | ABBOTT LABORATORIES (US) | 1991-01-30 | — | — | EP | disclosed |