SCHEMBL7305656

SCHEMBL7305656

Oc1cccc(C(Br)Br)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.52
CA12 O43570 2/20 0.52
ALDH1A1 P00352 2/20 0.52
CA2 P00918 2/20 0.52
CYP3A4 P08684 2/20 0.52
CA9 Q16790 2/20 0.52
CA14 Q9ULX7 2/20 0.52
CA5A P35218 1/20 0.52
HSD17B10 Q99714 1/20 0.52
CA5B Q9Y2D0 1/20 0.52
ADRB1 P08588 2/20 0.50
ADRA1A P35348 2/20 0.50
MIF P14174 1/20 0.50
HTR2A P28223 1/20 0.50
HTR2B P41595 1/20 0.50
SLC22A1 O15245 1/20 0.49
OPRM1 P35372 1/20 0.49
HIF1A Q16665 4/20 0.47
TSHR P16473 2/20 0.47
ESR1 P03372 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17926276 0.81 ADRB1 (0.57) LMNACA12ALDH1A1CA2CYP3A4
SCHEMBL5250314 0.81 PGK1 (0.42) ALDH1A1CA2CYP3A4CA9CA5A
SCHEMBL9616897 0.79 LMNA (0.58) LMNACA12ALDH1A1CA2CYP3A4
SCHEMBL19603047 0.79 LMNA (0.58) LMNACA12ALDH1A1CA2CYP3A4
SCHEMBL28234283 0.78 KYNU (0.53) LMNACA12ALDH1A1CA2CYP3A4
SCHEMBL2060109 0.77 ADRB1 (0.57) LMNACA12ALDH1A1CA2CYP3A4
SCHEMBL11590544 0.77 ADRB1 (0.69) LMNACA12ALDH1A1CA2CYP3A4
SCHEMBL670817 0.77 ADRB1 (0.57) LMNACA12ALDH1A1CA2CYP3A4
SCHEMBL1701121 0.76 ADRB1 (0.43) LMNACA12ALDH1A1CA2CYP3A4
SCHEMBL11218680 0.76 HIF1A (0.44) LMNACA12ALDH1A1CA2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9410088-B2 Phosphonate-substituted lignin as a flame retardant EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2016-08-09 US disclosed
US-20140378671-A1 PHOSPHONATE-SUBSTITUTED LIGNIN AS A FLAME RETARDANT CRESTLINE DIRECT FINANCE, L.P. 2014-12-25 US disclosed
US-8852468-B2 Phosphonate-substituted lignin as a flame retardant EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2014-10-07 US disclosed
US-20140235132-A1 PHOSPHONATE-SUBSTITUTED LIGNIN AS A FLAME RETARDANT EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2014-08-21 US disclosed
US-8747709-B2 Phosphonate-substituted lignin as a flame retardant EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2014-06-10 US disclosed
WO-2013165425-A1 PHOSPHONATE-SUBSTITUTED LIGNIN AS A FLAME RETARDANT EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2013-11-07 WO disclosed
US-20130292615-A1 PHOSPHONATE-SUBSTITUTED LIGNIN AS A FLAME RETARDANT EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2013-11-07 US disclosed
US-5629406-A AMINO ACID DERIVATIVES SANKYO COMPANY, LIMITED (JP) 1997-05-13 US disclosed
EP-0587311-A1 Peptides capable of inhibiting the activity of HIV protease, their preparation and their therapeutic use SANKYO COMPANY LIMITED (JP) 1994-03-16 EP disclosed