Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3E | A5X5Y0 | 5/20 | 0.48 |
| ▸ | HTR3B | O95264 | 5/20 | 0.48 |
| ▸ | HTR3A | P46098 | 5/20 | 0.48 |
| ▸ | HTR3D | Q70Z44 | 5/20 | 0.48 |
| ▸ | HTR3C | Q8WXA8 | 5/20 | 0.48 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
| ▸ | MTOR | P42345 | 2/20 | 0.44 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.44 |
| ▸ | CHRNG | P07510 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7305858 | 1.00 | HTR3E (0.48) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL7305238 | 0.85 | HTR3A (0.46) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL7305234 | 0.85 | HTR3A (0.46) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL7300915 | 0.81 | HTR3E (0.52) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL7430312 | 0.81 | HTR3A (0.58) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL7302698 | 0.76 | HTR3A (0.52) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL7302702 | 0.76 | HTR3A (0.52) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL7300934 | 0.75 | HTR3A (0.41) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL7286239 | 0.72 | HTR3E (0.47) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL4158228 | 0.72 | KDM5A (0.56) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0503844-B1 | Thienopyridine derivatives and pharmaceutical compositions containing them | KYOWA HAKKO KOGYO KK (JP) | 1994-08-03 | — | — | EP | disclosed |
| US-5155115-A | THIENOPYRIDINE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1992-10-13 | — | — | US | disclosed |
| EP-0503844-A1 | Thienopyridine derivatives and pharmaceutical compositions containing them | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1992-09-16 | — | — | EP | disclosed |