Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 3/20 | 0.41 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.41 |
| ▸ | HTR3B | O95264 | 2/20 | 0.41 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.41 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.41 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7300915 | 0.83 | HTR3E (0.52) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL7305858 | 0.75 | HTR3E (0.48) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL7305866 | 0.75 | HTR3E (0.48) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL7301719 | 0.69 | HTR3E (0.51) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL9525624 | 0.67 | HTR4 (0.48) | HTR3AHTR4MEN1KMT2A | |
| SCHEMBL7435902 | 0.67 | KMT2A (0.72) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL7308018 | 0.67 | HTR3A (0.50) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL7284925 | 0.66 | MEN1 (0.46) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL9524435 | 0.65 | SMN1; SMN2 (0.48) | HTR4MEN1KMT2A | |
| SCHEMBL7288748 | 0.65 | HTR3A (0.48) | HTR3AHTR3EHTR3BHTR3DHTR3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0503844-B1 | Thienopyridine derivatives and pharmaceutical compositions containing them | KYOWA HAKKO KOGYO KK (JP) | 1994-08-03 | — | — | EP | claimed |