Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | JAK3 | P52333 | 1/20 | 0.39 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | CCR2 | P41597 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | TACR1 | P25103 | 3/20 | 0.37 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.36 |
| ▸ | FASN | P49327 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7306203 | 1.00 | AR (0.39) | ARGPR119JAK2JAK3PTK2 | |
| SCHEMBL7297025 | 0.86 | KMT2A (0.41) | ARGPR119IRAK4 | |
| SCHEMBL7304305 | 0.83 | ITGB3 (0.37) | JAK3HRH3CCR2KCNH2TACR1 | |
| SCHEMBL7304309 | 0.83 | ITGB3 (0.37) | JAK3HRH3CCR2KCNH2TACR1 | |
| SCHEMBL7299171 | 0.83 | CCR2 (0.37) | JAK3HRH3CCR2KCNH2TACR1 | |
| SCHEMBL7299165 | 0.83 | CCR2 (0.37) | JAK3HRH3CCR2KCNH2TACR1 | |
| SCHEMBL7337695 | 0.82 | AR (0.44) | ARGPR119JAK2JAK3PTK2 | |
| SCHEMBL7305692 | 0.80 | ALK (0.40) | ARGPR119HRH3IRAK4KDR | |
| SCHEMBL7298324 | 0.77 | ALK (0.45) | IRAK4KDRALK | |
| SCHEMBL7300028 | 0.76 | CYP2C19 (0.33) | HRH3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0537980-A1 | Cyclohexaneacetic acid derivatives as inhibitors of fibrinogen-dependent blood platelet aggregation | GLAXO GROUP LIMITED (GB) | 1993-04-21 | — | — | EP | disclosed |