Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 4/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.37 |
| ▸ | LCK | P06239 | 2/20 | 0.37 |
| ▸ | JAK3 | P52333 | 2/20 | 0.37 |
| ▸ | BTK | Q06187 | 2/20 | 0.37 |
| ▸ | TACR1 | P25103 | 8/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | ESRRB | O95718 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESRRG | P62508 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7299165 | 1.00 | CCR2 (0.37) | CCR2KCNH2LCKJAK3BTK | |
| SCHEMBL7304309 | 0.90 | ITGB3 (0.37) | CCR2KCNH2LCKJAK3BTK | |
| SCHEMBL7304305 | 0.90 | ITGB3 (0.37) | CCR2KCNH2LCKJAK3BTK | |
| SCHEMBL7297485 | 0.86 | MEN1 (0.45) | HRH3CYP2C9KDM4EALDH1A1 | |
| SCHEMBL7306203 | 0.83 | AR (0.39) | CCR2KCNH2JAK3TACR1HRH3 | |
| SCHEMBL7306198 | 0.83 | AR (0.39) | CCR2KCNH2JAK3TACR1HRH3 | |
| SCHEMBL7345047 | 0.83 | ITGB3 (0.39) | KCNH2LCKJAK3BTKCYP2C9 | |
| SCHEMBL7293154 | 0.81 | ALDH1A1 (0.34) | HRH3KDM4EALDH1A1 | |
| SCHEMBL7297503 | 0.78 | L3MBTL1 (0.36) | KDM4EALDH1A1 | |
| SCHEMBL7296131 | 0.75 | AOC3 (0.38) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0537980-A1 | Cyclohexaneacetic acid derivatives as inhibitors of fibrinogen-dependent blood platelet aggregation | GLAXO GROUP LIMITED (GB) | 1993-04-21 | — | — | EP | disclosed |