Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 2/20 | 0.46 |
| ▸ | CTSK | P43235 | 2/20 | 0.46 |
| ▸ | CTSC | P53634 | 7/20 | 0.41 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.37 |
| ▸ | EBP | Q15125 | 2/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
| ▸ | CTSL | P07711 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | FNTA | P49354 | 2/20 | 0.34 |
| ▸ | FNTB | P49356 | 2/20 | 0.34 |
| ▸ | PGGT1B | P53609 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7304422 | 0.84 | CTSL (0.50) | CTSSCTSKEBPSIGMAR1CTSL | |
| SCHEMBL7309770 | 0.82 | EBP (0.44) | CTSSCTSKEBPSIGMAR1CTSL | |
| SCHEMBL7307758 | 0.81 | EBP (0.43) | CTSSCTSKEBPSIGMAR1CTSL | |
| SCHEMBL7314206 | 0.81 | EBP (0.43) | CTSSCTSKEBPSIGMAR1CTSL | |
| SCHEMBL7313580 | 0.81 | FNTA (0.39) | CTSSCTSKEBPSIGMAR1CTSL | |
| SCHEMBL7306274 | 0.81 | EBP (0.39) | CTSSCTSKEBPSIGMAR1CTSL | |
| SCHEMBL7316235 | 0.81 | FNTA (0.39) | CTSSCTSKEBPSIGMAR1CTSL | |
| SCHEMBL7312048 | 0.81 | FNTA (0.39) | CTSSCTSKEBPSIGMAR1CTSL | |
| SCHEMBL7307137 | 0.80 | REN (0.44) | CTSL | |
| SCHEMBL7304195 | 0.79 | EBP (0.41) | CTSSCTSKEBPSIGMAR1CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1041064-A2 | N-substituted alpha aminoacid amides as calcium channel modulators | ELI LILLY AND COMPANY LIMITED (GB) | 2000-10-04 | — | — | EP | disclosed |
| EP-0805147-A1 | Novel N-substituted alpha aminoacid amides as calcium channel modulators | LILLY INDUSTRIES LIMITED (GB) | 1997-11-05 | — | — | EP | disclosed |