Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 15/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 14/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 9/20 | 0.49 |
| ▸ | MAPT | P10636 | 8/20 | 0.49 |
| ▸ | HPGD | P15428 | 6/20 | 0.49 |
| ▸ | TSHR | P16473 | 6/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 6/20 | 0.47 |
| ▸ | USP2 | O75604 | 4/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | CASP1 | P29466 | 3/20 | 0.47 |
| ▸ | CASP7 | P55210 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.45 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7313419 | 0.89 | PDE3B (0.48) | ALDH1A1KDM4EHSD17B10MAPTHPGD | |
| SCHEMBL7316158 | 0.86 | ALDH1A1 (0.47) | ALDH1A1KDM4EHSD17B10MAPTHPGD | |
| SCHEMBL7303943 | 0.80 | ALDH1A1 (0.53) | ALDH1A1KDM4EHSD17B10MAPTHPGD | |
| SCHEMBL7318076 | 0.80 | KCNH2 (0.42) | ALDH1A1KDM4EHSD17B10MAPTHPGD | |
| SCHEMBL7309768 | 0.79 | PDE3B (0.40) | ALDH1A1KDM4EHSD17B10MAPTHPGD | |
| SCHEMBL7317529 | 0.79 | ALDH1A1 (0.48) | ALDH1A1KDM4EHSD17B10MAPTHPGD | |
| SCHEMBL3373971 | 0.79 | MAOB (0.65) | ALDH1A1KDM4EHSD17B10HPGDACHE | |
| SCHEMBL7347245 | 0.79 | ALDH1A1 (0.48) | ALDH1A1KDM4EHSD17B10MAPTHPGD | |
| SCHEMBL7307423 | 0.76 | ALDH1A1 (0.40) | ALDH1A1KDM4EHSD17B10MAPTHPGD | |
| SCHEMBL7310025 | 0.74 | PKM (0.44) | ALDH1A1KDM4EHSD17B10HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4277479-A | ANTI-ASTHMATIC, HYPOTENSIVE, ANTI-ULCER, ANTIINFLAMMATORY, VASODILATION, ENZYME INHIBITORS, ANTICOAGULANTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1981-07-07 | — | — | US | disclosed |