Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 17/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 16/20 | 0.47 |
| ▸ | MAPT | P10636 | 11/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 9/20 | 0.47 |
| ▸ | TSHR | P16473 | 7/20 | 0.47 |
| ▸ | HPGD | P15428 | 6/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 8/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.45 |
| ▸ | GAA | P10253 | 4/20 | 0.45 |
| ▸ | USP2 | O75604 | 4/20 | 0.45 |
| ▸ | CASP1 | P29466 | 4/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | CASP7 | P55210 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7306333 | 0.86 | ALDH1A1 (0.49) | ALDH1A1KDM4EMAPTHSD17B10TSHR | |
| SCHEMBL7316667 | 0.85 | ALDH1A1 (0.42) | ALDH1A1KDM4EMAPTHSD17B10TSHR | |
| SCHEMBL7313419 | 0.83 | PDE3B (0.48) | ALDH1A1KDM4EMAPTHSD17B10TSHR | |
| SCHEMBL7317621 | 0.81 | ALDH1A1 (0.38) | ALDH1A1KDM4EMAPTHSD17B10TSHR | |
| SCHEMBL7311227 | 0.81 | KDM4E (0.43) | ALDH1A1KDM4EMAPTHSD17B10TSHR | |
| SCHEMBL7319001 | 0.78 | PDE3B (0.49) | ALDH1A1KDM4EMAPTHSD17B10TSHR | |
| SCHEMBL7311963 | 0.77 | MAOA (0.53) | ALDH1A1TSHRNPSR1SMN1; SMN2LMNA | |
| SCHEMBL7317529 | 0.76 | ALDH1A1 (0.48) | ALDH1A1KDM4EMAPTHSD17B10TSHR | |
| SCHEMBL7318076 | 0.75 | KCNH2 (0.42) | ALDH1A1KDM4EMAPTHSD17B10TSHR | |
| SCHEMBL7303943 | 0.75 | ALDH1A1 (0.53) | ALDH1A1KDM4EMAPTHSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4277479-A | ANTI-ASTHMATIC, HYPOTENSIVE, ANTI-ULCER, ANTIINFLAMMATORY, VASODILATION, ENZYME INHIBITORS, ANTICOAGULANTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1981-07-07 | — | — | US | disclosed |