Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | PDE5A | O76074 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | PTAFR | P25105 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7316070 | 0.90 | ALDH1A1 (0.43) | HTTALDH1A1KMT2ALMNAPDE3B | |
| SCHEMBL7307849 | 0.90 | KCNH2 (0.47) | ALDH1A1KMT2ALMNAPDE3BPDE3A | |
| SCHEMBL7309366 | 0.86 | HSD11B1 (0.44) | ALDH1A1KMT2APDE3BPDE3AHSD11B1 | |
| SCHEMBL7313419 | 0.84 | PDE3B (0.48) | PKMHTTALDH1A1KMT2ALMNA | |
| SCHEMBL7320251 | 0.84 | MAPT (0.48) | ALDH1A1KMT2ALMNAPDE3BPDE3A | |
| SCHEMBL7312752 | 0.83 | HCAR1 (0.40) | PKMHTTALDH1A1KMT2ALMNA | |
| SCHEMBL7303943 | 0.83 | ALDH1A1 (0.53) | ALDH1A1KMT2ALMNAPDE3BPDE3A | |
| SCHEMBL7317769 | 0.83 | PDE3B (0.45) | ALDH1A1KMT2ALMNAPDE3BPDE3A | |
| SCHEMBL7316667 | 0.82 | ALDH1A1 (0.42) | PKMHTTNLRP3ALDH1A1KMT2A | |
| SCHEMBL7314477 | 0.82 | PPARA (0.45) | PKMHTTNLRP3ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4277479-A | ANTI-ASTHMATIC, HYPOTENSIVE, ANTI-ULCER, ANTIINFLAMMATORY, VASODILATION, ENZYME INHIBITORS, ANTICOAGULANTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1981-07-07 | — | — | US | claimed |
| US-4277479-A | ANTI-ASTHMATIC, HYPOTENSIVE, ANTI-ULCER, ANTIINFLAMMATORY, VASODILATION, ENZYME INHIBITORS, ANTICOAGULANTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1981-07-07 | — | — | US | disclosed |