Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.52 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 3/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | PLG | P00747 | 1/20 | 0.42 |
| ▸ | PLAU | P00749 | 1/20 | 0.42 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7297140 | 0.94 | MCHR1 (0.47) | MCHR1ITGB3ITGA2BRORCNAMPT | |
| SCHEMBL7298694 | 0.86 | ITGB3 (0.47) | MCHR1ITGB3ITGA2B | |
| SCHEMBL7298316 | 0.82 | ITGB3 (0.43) | MCHR1ITGB3ITGA2BF2PLG | |
| SCHEMBL7303281 | 0.82 | PGR (0.40) | MCHR1MEN1NPC1KMT2A | |
| SCHEMBL7395359 | 0.80 | RAB9A (0.43) | MCHR1ITGB3ITGA2BNPC1RAB9A | |
| SCHEMBL7312190 | 0.80 | MCHR1 (0.47) | MCHR1ITGB3ITGA2BLRRK2RORC | |
| SCHEMBL7442101 | 0.80 | RAB9A (0.45) | MCHR1ITGB3ITGA2BNPC1RAB9A | |
| SCHEMBL7431007 | 0.80 | ITGB3 (0.41) | ITGB3ITGA2BMEN1NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL7388899 | 0.80 | RAB9A (0.42) | MCHR1ITGB3ITGA2BNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL7391203 | 0.79 | ITGB3 (0.41) | ITGB3ITGA2BMEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760364-B1 | Amidine derivatives and platelet aggregation inhibitor containing the same | MITSUI CHEMICALS INC (JP) | 2000-07-19 | — | — | EP | disclosed |
| EP-0709370-B1 | Bicyclic compounds useful as platelet aggregation inhibitors | MITSUI CHEMICALS INC (JP) | 1999-01-13 | — | — | EP | disclosed |
| US-5719145-A | FIBRINOGEN ANTAGONIST FOR TREATMENT OF THROMBOSIS, RESTENOSIS AFTER ANGIOPLASTY OR CORONARY RECANALIZATION; WATER SOLUBILITY, ORAL ADMINISTRATION | MITSUI TOATSU CHEMICALS, INC. (JP) | 1998-02-17 | — | — | US | disclosed |
| US-5629321-A | FIBRINOGEN ANTAGONIST | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-05-13 | — | — | US | disclosed |
| EP-0760364-A2 | Amidine derivatives and platelet aggregation inhibitor containing the same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1997-03-05 | — | — | EP | disclosed |
| EP-0709370-A1 | Bicyclic compounds useful as platelet aggregation inhibitors | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-05-01 | — | — | EP | disclosed |