Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 3/20 | 0.39 |
| ▸ | PPARA | Q07869 | 3/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | ITK | Q08881 | 7/20 | 0.36 |
| ▸ | TXK | P42681 | 1/20 | 0.36 |
| ▸ | MLYCD | O95822 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | NSD2 | O96028 | 2/20 | 0.34 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.34 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.33 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.33 |
| ▸ | PRKCG | P05129 | 2/20 | 0.33 |
| ▸ | PHKG2 | P15735 | 2/20 | 0.33 |
| ▸ | MARK3 | P27448 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7299593 | 0.83 | ALDH1A1 (0.40) | PPARDPPARAMCHR1ITKMLYCD | |
| SCHEMBL7306389 | 0.82 | MEN1 (0.35) | KMT2AMEN1ALDH1A1TP53MAPT | |
| SCHEMBL7306501 | 0.82 | MCHR1 (0.52) | MCHR1KMT2AMEN1NPC1 | |
| SCHEMBL7297140 | 0.82 | MCHR1 (0.47) | MCHR1MLYCD | |
| SCHEMBL7302144 | 0.81 | ITGB3 (0.49) | — | |
| SCHEMBL7295951 | 0.80 | PGR (0.39) | PGRPPARDPPARAMCHR1KMT2A | |
| SCHEMBL7397367 | 0.79 | SMN1; SMN2 (0.33) | KMT2AMEN1NPC1ALDH1A1MAPT | |
| SCHEMBL7394074 | 0.79 | MAPT (0.43) | KMT2AMEN1NPC1ALDH1A1MAPT | |
| SCHEMBL7304733 | 0.77 | ACHE (0.37) | PPARD | |
| SCHEMBL7300477 | 0.77 | PPARA (0.49) | PPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709370-B1 | Bicyclic compounds useful as platelet aggregation inhibitors | MITSUI CHEMICALS INC (JP) | 1999-01-13 | — | — | EP | disclosed |
| US-5629321-A | FIBRINOGEN ANTAGONIST | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-05-13 | — | — | US | disclosed |
| EP-0709370-A1 | Bicyclic compounds useful as platelet aggregation inhibitors | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-05-01 | — | — | EP | disclosed |