Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 5/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.45 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL7304901 | 0.93 | KDM4E (0.46) | ADORA2AADORA1ADORA2BADORA3KDM4E | |
| SCHEMBL7295510 | 0.85 | TAAR1 (0.46) | ADORA2AADORA1ADORA2BADORA3KDM4E | |
| SCHEMBL7165172 | 0.85 | NOS2 (0.49) | ADORA2AADORA1ADORA3KDM4ENPC1 | |
| SCHEMBL7167684 | 0.80 | NOS2 (0.53) | KDM4EALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7299551 | 0.79 | KDM4E (0.46) | ADORA2AADORA1ADORA2BADORA3KDM4E | |
| SCHEMBL20324683 | 0.76 | KDM4E (0.47) | ADORA2AADORA1ADORA2BKDM4EALDH1A1 | |
| SCHEMBL7303142 | 0.76 | ADORA2A (0.42) | ADORA2AADORA1ADORA2BADORA3KDM4E | |
| SCHEMBL7305553 | 0.76 | ADORA2A (0.44) | ADORA2AADORA1ADORA2BKDM4EALDH1A1 | |
| SCHEMBL7296179 | 0.74 | ESR2 (0.47) | KDM4EALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL7298270 | 0.74 | RPS6KB1 (0.41) | ADORA2AADORA1KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0604353-B1 | Benzimidazole compounds, their preparation and use | NEUROSEARCH AS (DK) | 1998-07-01 | — | — | EP | claimed |