Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 4/20 | 0.44 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7299551 | 0.85 | KDM4E (0.46) | ADORA2AADORA1MAPTSMN1; SMN2RPS6KB1 | |
| SCHEMBL7303142 | 0.82 | ADORA2A (0.42) | ADORA2AADORA1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL7295510 | 0.77 | TAAR1 (0.46) | ADORA2AADORA1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL7306716 | 0.76 | ADORA2A (0.45) | ADORA2AADORA1MAPTSMN1; SMN2RPS6KB1 | |
| SCHEMBL31452291 | 0.73 | KDM4E (0.48) | MAPTSMN1; SMN2RPS6KB1KDM4ETSHR | |
| SCHEMBL6438855 | 0.72 | ALDH1A1 (0.63) | MAPTSMN1; SMN2RPS6KB1KDM4ELMNA | |
| Oxalic Acid SCHEMBL7304901 | 0.71 | KDM4E (0.46) | ADORA2AADORA1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL7305407 | 0.71 | ADORA2A (0.49) | ADORA2APIK3R1PIK3CAADORA1MAPT | |
| SCHEMBL7295792 | 0.70 | RPS6KB1 (0.38) | MAPTRPS6KB1LMNATSHRALDH1A1 | |
| SCHEMBL15214855 | 0.69 | L3MBTL1 (0.56) | ADORA2AADORA1MAPTSMN1; SMN2RPS6KB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0604353-B1 | Benzimidazole compounds, their preparation and use | NEUROSEARCH AS (DK) | 1998-07-01 | — | — | EP | claimed |
| US-5441969-A | Imidazole compounds, their preparation and use | NEUROSEARCH A/S (DK) | 1995-08-15 | — | — | US | claimed |
| EP-0604353-A1 | Benzimidazole compounds, their preparation and use | NEUROSEARCH A/S (DK) | 1994-06-29 | — | — | EP | claimed |
| EP-0604353-B1 | Benzimidazole compounds, their preparation and use | NEUROSEARCH AS (DK) | 1998-07-01 | — | — | EP | disclosed |
| US-5441969-A | Imidazole compounds, their preparation and use | NEUROSEARCH A/S (DK) | 1995-08-15 | — | — | US | disclosed |
| EP-0604353-A1 | Benzimidazole compounds, their preparation and use | NEUROSEARCH A/S (DK) | 1994-06-29 | — | — | EP | disclosed |