Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | THRA | P10827 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7306823 | 0.86 | ALDH1A1 (0.38) | ALDH1A1POLBTHRAATMSMN1; SMN2 | |
| SCHEMBL7306725 | 0.80 | ALDH1A1 (0.40) | ALDH1A1POLBTHRAATMSMN1; SMN2 | |
| SCHEMBL7306817 | 0.71 | ALDH1A1 (0.39) | ALDH1A1POLBTHRAATMSMN1; SMN2 | |
| SCHEMBL7314387 | 0.67 | PDE3B (0.42) | ALDH1A1POLBTHRASMN1; SMN2LMNA | |
| SCHEMBL7309039 | 0.67 | ALDH1A1 (0.40) | ALDH1A1POLBTHRAATMSMN1; SMN2 | |
| SCHEMBL7313370 | 0.67 | ALDH1A1 (0.42) | ALDH1A1THRAATMSMN1; SMN2KDM4E | |
| SCHEMBL29271874 | 0.66 | FOLH1 (0.48) | ALDH1A1POLBKDM4ELMNAMEN1 | |
| SCHEMBL10377117 | 0.65 | PDE3B (0.42) | ALDH1A1THRASMN1; SMN2KDM4ELMNA | |
| SCHEMBL19953661 | 0.64 | POLQ (0.49) | ALDH1A1POLBKDM4ELMNAMEN1 | |
| SCHEMBL15480457 | 0.64 | ALDH1A1 (0.50) | ALDH1A1POLBKDM4ELMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |