Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | THRA | P10827 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7306731 | 0.86 | ALDH1A1 (0.38) | ALDH1A1THRAATMSMN1; SMN2KDM4E | |
| SCHEMBL7306817 | 0.82 | ALDH1A1 (0.39) | ALDH1A1THRAATMSMN1; SMN2KDM4E | |
| SCHEMBL7317244 | 0.70 | PDE3B (0.41) | ALDH1A1THRAATMSMN1; SMN2KDM4E | |
| SCHEMBL7314934 | 0.70 | ALDH1A1 (0.41) | ALDH1A1THRAATMSMN1; SMN2KDM4E | |
| SCHEMBL7317466 | 0.69 | PDE3B (0.46) | ALDH1A1THRAATMSMN1; SMN2KDM4E | |
| SCHEMBL7306725 | 0.68 | ALDH1A1 (0.40) | ALDH1A1THRAATMSMN1; SMN2KDM4E | |
| SCHEMBL7309039 | 0.67 | ALDH1A1 (0.40) | ALDH1A1THRAATMSMN1; SMN2KDM4E | |
| SCHEMBL29271874 | 0.66 | FOLH1 (0.48) | ALDH1A1KDM4EPOLBLMNAMEN1 | |
| SCHEMBL14470578 | 0.66 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2KDM4EPOLBLMNA | |
| SCHEMBL7307955 | 0.65 | L3MBTL1 (0.43) | ALDH1A1THRAKDM4ETHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |