Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 10/20 | 0.60 |
| ▸ | ITGA2B | P08514 | 10/20 | 0.60 |
| ▸ | P2RY12 | Q9H244 | 4/20 | 0.39 |
| ▸ | CCR1 | P32246 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7310657 | 0.90 | ITGB3 (0.57) | ITGB3ITGA2BP2RY12CCR1 | |
| SCHEMBL7310059 | 0.88 | ITGB3 (0.64) | ITGB3ITGA2BP2RY12CCR1 | |
| SCHEMBL7317008 | 0.87 | ITGB3 (0.45) | ITGB3ITGA2BP2RY12KDM4ECHRM2 | |
| SCHEMBL7317003 | 0.87 | ITGB3 (0.43) | ITGB3ITGA2BP2RY12KDM4ECHRM2 | |
| SCHEMBL7307131 | 0.83 | ITGB3 (0.41) | ITGB3ITGA2BKDM4E | |
| SCHEMBL7310664 | 0.79 | ITGB3 (0.38) | ITGB3ITGA2B | |
| SCHEMBL7310063 | 0.79 | ITGB3 (0.40) | ITGB3ITGA2B | |
| SCHEMBL7315714 | 0.77 | ITGB3 (0.75) | ITGB3ITGA2BP2RY12CCR1KDM4E | |
| Sibrafiban SCHEMBL27618015 | 0.74 | ITGB3 (1.00) | ITGB3ITGA2BLMNA | |
| Sibrafiban SCHEMBL50759 | 0.74 | ITGB3 (1.00) | ITGB3ITGA2BLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0741133-A2 | Adhesion receptor antagonists | MERCK PATENT GmbH (DE) | 1996-11-06 | — | — | EP | disclosed |