Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.41 |
| ▸ | SCN4A | P35499 | 2/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
| ▸ | HPN | P05981 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.40 |
| ▸ | HGFAC | Q04756 | 1/20 | 0.40 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.40 |
| ▸ | FPR2 | P25090 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7309474 | 0.95 | ALDH1A1 (0.44) | ALDH1A1MAPTPARP1TMEM97SIGMAR1 | |
| SCHEMBL7303582 | 0.93 | ACHE (0.45) | ALDH1A1MAPTCHRM4 | |
| SCHEMBL7308889 | 0.92 | ACHE (0.42) | CHRM4DRD2DRD4 | |
| SCHEMBL7316436 | 0.92 | ACHE (0.43) | CHRM4DRD2DRD4 | |
| SCHEMBL7314130 | 0.91 | ALDH1A1 (0.43) | ALDH1A1MAPTCACNA1GTMEM97SIGMAR1 | |
| SCHEMBL7310156 | 0.91 | ALDH1A1 (0.43) | ALDH1A1MAPTCACNA1GTMEM97SIGMAR1 | |
| SCHEMBL7314325 | 0.91 | ALDH1A1 (0.43) | ALDH1A1MAPTCACNA1GTMEM97SIGMAR1 | |
| SCHEMBL7308770 | 0.90 | LTA4H (0.44) | CACNA1GPARP1TMEM97SIGMAR1 | |
| SCHEMBL7311490 | 0.89 | SIGMAR1 (0.42) | PARP1TMEM97SIGMAR1CHRM4F10 | |
| SCHEMBL7311502 | 0.88 | ACHE (0.43) | ALDH1A1MAPTCHRM4DRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776937-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-07-07 | — | — | US | disclosed |
| EP-0711770-A1 | Antagonists of adhesion receptors | MERCK PATENT GmbH (DE) | 1996-05-15 | — | — | EP | disclosed |