Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 4/20 | 0.55 |
| ▸ | XIAP | P98170 | 9/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CTSH | P09668 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CTSK | P43235 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7307439 | 1.00 | CTSC (0.55) | CTSCXIAPLMNAMEN1KMT2A | |
| SCHEMBL9115406 | 0.85 | KDM4E (0.55) | CTSCLMNAMEN1KMT2ACYP1A2 | |
| SCHEMBL7313780 | 0.84 | POLB (0.55) | XIAPLMNATSHRNPSR1POLB | |
| SCHEMBL7313784 | 0.84 | POLB (0.55) | XIAPLMNATSHRNPSR1POLB | |
| SCHEMBL7307216 | 0.84 | CTSC (0.47) | CTSCXIAPLMNAMEN1KMT2A | |
| SCHEMBL7317027 | 0.83 | LARS1 (0.56) | LMNAMEN1KMT2ATSHRPOLB | |
| SCHEMBL7657880 | 0.83 | LARS1 (0.56) | LMNAMEN1KMT2ATSHRPOLB | |
| SCHEMBL7314845 | 0.82 | MEN1 (0.56) | LMNAMEN1KMT2ATSHRSMN1; SMN2 | |
| SCHEMBL8615988 | 0.82 | MEN1 (0.56) | LMNAMEN1KMT2ATSHRSMN1; SMN2 | |
| SCHEMBL7314855 | 0.82 | MEN1 (0.56) | LMNAMEN1KMT2ATSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1041064-A2 | N-substituted alpha aminoacid amides as calcium channel modulators | ELI LILLY AND COMPANY LIMITED (GB) | 2000-10-04 | — | — | EP | disclosed |
| EP-0805147-A1 | Novel N-substituted alpha aminoacid amides as calcium channel modulators | LILLY INDUSTRIES LIMITED (GB) | 1997-11-05 | — | — | EP | disclosed |