Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | METAP2 | P50579 | 4/20 | 0.44 |
| ▸ | METAP1 | P53582 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TLR2 | O60603 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.41 |
| ▸ | XIAP | P98170 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7307442 | 0.84 | CTSC (0.55) | CTSCLMNATSHRNPSR1MEN1 | |
| SCHEMBL7307439 | 0.84 | CTSC (0.55) | CTSCLMNATSHRNPSR1MEN1 | |
| SCHEMBL7313784 | 0.79 | POLB (0.55) | LMNATSHRNPSR1XIAP | |
| SCHEMBL7313780 | 0.79 | POLB (0.55) | LMNATSHRNPSR1XIAP | |
| SCHEMBL7317027 | 0.78 | LARS1 (0.56) | LMNATSHRMEN1KMT2A | |
| SCHEMBL7657880 | 0.78 | LARS1 (0.56) | LMNATSHRMEN1KMT2A | |
| SCHEMBL7303552 | 0.78 | CTSC (0.48) | CTSCLMNATSHR | |
| SCHEMBL12340094 | 0.76 | CTSC (0.61) | CTSCSMN1; SMN2XIAP | |
| SCHEMBL8359814 | 0.76 | CTSC (0.61) | CTSCSMN1; SMN2XIAP | |
| SCHEMBL7316402 | 0.75 | CTRB1 (0.63) | LMNATSHRMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1041064-A2 | N-substituted alpha aminoacid amides as calcium channel modulators | ELI LILLY AND COMPANY LIMITED (GB) | 2000-10-04 | — | — | EP | disclosed |
| EP-0805147-A1 | Novel N-substituted alpha aminoacid amides as calcium channel modulators | LILLY INDUSTRIES LIMITED (GB) | 1997-11-05 | — | — | EP | disclosed |