Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 9/20 | 0.35 |
| ▸ | CNR1 | P21554 | 7/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7320749 | 0.87 | MAOB (0.39) | LMNACNR2CNR1KDM4E | |
| SCHEMBL7311424 | 0.86 | LMNA (0.37) | LMNACNR2CNR1KDM4EALDH1A1 | |
| SCHEMBL7307607 | 0.84 | LMNA (0.36) | SIRT3LMNACNR2CNR1KDM4E | |
| SCHEMBL10377207 | 0.81 | LMNA (0.40) | LMNAKDM4EITGB3ITGA2BALDH1A1 | |
| SCHEMBL7310463 | 0.75 | SIRT3 (0.39) | SIRT3LMNACNR2CNR1KDM4E | |
| SCHEMBL7307614 | 0.75 | KDM4E (0.37) | KDM4EITGB3ITGA2BALDH1A1MAPT | |
| SCHEMBL7316032 | 0.72 | SIRT3 (0.41) | SIRT3LMNAKDM4EALDH1A1MAPT | |
| SCHEMBL7320743 | 0.71 | MAOB (0.38) | LMNAKDM4EALDH1A1 | |
| SCHEMBL7311419 | 0.70 | ALDH1A1 (0.35) | LMNAKDM4EITGB3ITGA2BALDH1A1 | |
| SCHEMBL7310467 | 0.69 | ALDH1A1 (0.48) | LMNAKDM4EALDH1A1MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |