Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA3 | P34903 | 6/20 | 0.56 |
| ▸ | GABRA2 | P47869 | 6/20 | 0.56 |
| ▸ | GABRG2 | P18507 | 8/20 | 0.52 |
| ▸ | GABRB3 | P28472 | 8/20 | 0.52 |
| ▸ | GABRA5 | P31644 | 6/20 | 0.50 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.50 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.50 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.50 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7317652 | 0.89 | GABRA3 (0.60) | GABRA3GABRA2GABRG2GABRB3GABRA5 | |
| SCHEMBL11628537 | 0.81 | GABRG2 (0.66) | GABRA3GABRA2GABRG2GABRB3GABRA5 | |
| SCHEMBL7310012 | 0.80 | GABRG2 (0.62) | GABRA3GABRA2GABRG2GABRB3GABRA5 | |
| SCHEMBL7722534 | 0.79 | GABRG2 (0.75) | GABRA3GABRA2GABRG2GABRB3GABRA5 | |
| SCHEMBL7317878 | 0.78 | GABRA2 (0.61) | GABRA3GABRA2GABRG2GABRB3GABRA5 | |
| SCHEMBL7383286 | 0.78 | GABRG2 (0.55) | GABRA3GABRA2GABRG2GABRB3GABRA5 | |
| SCHEMBL7353479 | 0.78 | GABRA3 (0.57) | GABRA3GABRA2GABRG2GABRB3GABRA5 | |
| SCHEMBL14282643 | 0.77 | GABRG2 (0.66) | GABRA3GABRA2GABRG2GABRB3GABRA5 | |
| SCHEMBL7317516 | 0.76 | GABRA3 (0.48) | GABRA3GABRA2GABRG2GABRB3GABRA5 | |
| SCHEMBL7285884 | 0.76 | GABRA3 (0.47) | GABRA3GABRA2GABRG2GABRB3GABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4440685-A | MUSCLE RELAXANTS, SEDATIVES, ANTICONVULSANTS | HOFFMANN-LA ROCHE INC. (US) | 1984-04-03 | — | — | US | disclosed |
| US-4425272-A | ANTICONVULSANTS, MUSCLE RELAXANTS, SEDATIVES | HOFFMANN-LA ROCHE INC. (US) | 1984-01-10 | — | — | US | disclosed |