Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 5/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CCR3 | P51677 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4294891 | 0.94 | HTR4 (0.55) | HTR4CYP1A2CYP2C9ALOX15NFKB1 | |
| Fumaric Acid SCHEMBL2942179 | 0.90 | HTR4 (0.51) | HTR4CYP1A2CYP2C9ALOX15NFKB1 | |
| SCHEMBL9704182 | 0.87 | HTR4 (0.63) | HTR4CYP1A2CYP2C9ALOX15NFKB1 | |
| SCHEMBL9341470 | 0.85 | HTR4 (0.50) | HTR4PMP22NPSR1KCNH2HTR7 | |
| SCHEMBL7308950 | 0.85 | KDM1A (0.46) | HTR4CYP1A2CYP2C9ALOX15NFKB1 | |
| SCHEMBL7304868 | 0.83 | SLC6A2 (0.47) | MAPTHTR7RAB9ASLC6A2SLC6A3 | |
| SCHEMBL7300755 | 0.82 | KDM4E (0.46) | HTR4MAPTHTR7SLC6A2SLC6A3 | |
| SCHEMBL7309279 | 0.82 | KDM1A (0.45) | HTR4CYP1A2CYP2C9MAPTHTR7 | |
| SCHEMBL7304670 | 0.82 | KDM1A (0.46) | MAPTHTR7SMN1; SMN2AGTR1 | |
| SCHEMBL7303226 | 0.81 | CYP2C9 (0.49) | HTR4CYP1A2CYP2C9ALOX15NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0501322-B1 | 3-Piperidinylmethylcarboxylate substituted indoles | GLAXO GROUP LTD (GB) | 1996-09-04 | — | — | EP | claimed |