Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 5/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.63 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.63 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.63 |
| ▸ | BCHE | P06276 | 2/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4294891 | 0.92 | HTR4 (0.55) | HTR4CYP1A2CYP2C9ALOX15NFKB1 | |
| Fumaric Acid SCHEMBL2942179 | 0.88 | HTR4 (0.51) | HTR4CYP1A2CYP2C9ALOX15NFKB1 | |
| SCHEMBL7307824 | 0.87 | HTR4 (0.49) | HTR4CYP1A2CYP2C9ALOX15NFKB1 | |
| SCHEMBL7324773 | 0.86 | HTR4 (0.69) | HTR4CYP1A2CYP2C9ALOX15NFKB1 | |
| SCHEMBL7308950 | 0.83 | KDM1A (0.46) | HTR4CYP1A2CYP2C9ALOX15NFKB1 | |
| SCHEMBL7304868 | 0.80 | SLC6A2 (0.47) | SLC6A2SLC6A3 | |
| SCHEMBL7303226 | 0.80 | CYP2C9 (0.49) | HTR4CYP1A2CYP2C9ALOX15NFKB1 | |
| SCHEMBL7301718 | 0.79 | HTR4 (0.62) | HTR4CYP1A2CYP2C9ALOX15NFKB1 | |
| SCHEMBL4294889 | 0.78 | HTR4 (0.61) | HTR4CYP1A2CYP2C9ALOX15NFKB1 | |
| SCHEMBL1502039 | 0.78 | HTR4 (1.00) | HTR4CYP1A2CYP2C9ALOX15NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992014727-A1 | 3-PIPERIDINYLMETHYLCARBOXYLATE SUBSTITUTED INDOLES | GLAXO GROUP LIMITED (GB) | 1992-09-03 | — | — | WO | disclosed |