Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.49 |
| ▸ | BACE1 | P56817 | 11/20 | 0.49 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.47 |
| ▸ | CTSS | P25774 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 1/20 | 0.47 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.47 |
| ▸ | KLK7 | P49862 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7316663 | 0.90 | CA2 (0.53) | BACE1BACE2CTSSCTSKKLK5 | |
| SCHEMBL7317918 | 0.85 | CTSK (0.46) | BACE1CTSSCTSKKLK5KLK7 | |
| SCHEMBL7305458 | 0.85 | CTSK (0.46) | BACE1CTSSCTSKKLK5KLK7 | |
| SCHEMBL31291804 | 0.81 | CTSK (0.65) | ANPEPBACE1BACE2CTSSCTSK | |
| SCHEMBL7317017 | 0.81 | CTSK (0.47) | BACE1BACE2CTSSCTSKKLK5 | |
| SCHEMBL6619713 | 0.81 | KLK7 (0.58) | ANPEPBACE1CTSSCTSKKLK5 | |
| SCHEMBL6619716 | 0.81 | KLK7 (0.58) | ANPEPBACE1CTSSCTSKKLK5 | |
| SCHEMBL526076 | 0.81 | ANPEP (0.58) | ANPEPALDH1A1LMNA | |
| SCHEMBL526077 | 0.81 | ANPEP (0.58) | ANPEPALDH1A1LMNA | |
| SCHEMBL7311059 | 0.81 | CTSK (0.47) | BACE1BACE2CTSSCTSKKLK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1041064-A2 | N-substituted alpha aminoacid amides as calcium channel modulators | ELI LILLY AND COMPANY LIMITED (GB) | 2000-10-04 | — | — | EP | disclosed |
| EP-0805147-A1 | Novel N-substituted alpha aminoacid amides as calcium channel modulators | LILLY INDUSTRIES LIMITED (GB) | 1997-11-05 | — | — | EP | disclosed |