Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.34 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.33 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | RBP4 | P02753 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7307903 | 0.74 | ITGB3 (0.57) | ITGB3ITGA2B | |
| SCHEMBL7298275 | 0.74 | GAA (0.49) | SIGMAR1ITGB3ITGA2BSMN1; SMN2 | |
| SCHEMBL22363784 | 0.74 | PDK1 (0.32) | SIGMAR1SLC6A9ITGB3ITGA2BSMYD3 | |
| SCHEMBL20542495 | 0.72 | ALDH1A1 (0.32) | SIGMAR1SLC6A9SMN1; SMN2 | |
| SCHEMBL21823215 | 0.72 | ALDH1A1 (0.32) | SIGMAR1SLC6A9SMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL29777017 | 0.71 | DPP8 (0.33) | — | |
| Tromethamine SCHEMBL7211844 | 0.69 | HSD17B10 (0.32) | SLC6A9 | |
| SCHEMBL9891877 | 0.67 | LMNA (0.38) | SLC6A9 | |
| SCHEMBL437880 | 0.67 | — | — | |
| SCHEMBL11032090 | 0.67 | LMNA (0.56) | SIGMAR1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0445796-B1 | Derivatives of acetic acid containing peptide bonds | HOFFMANN LA ROCHE (CH) | 1998-06-17 | — | — | EP | disclosed |
| EP-0445796-A2 | Derivatives of acetic acid | F. HOFFMANN-LA ROCHE AG (CH) | 1991-09-11 | — | — | EP | disclosed |