Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.43 |
| ▸ | ADCY6 | O43306 | 1/20 | 0.43 |
| ▸ | ADCY3 | O60266 | 1/20 | 0.43 |
| ▸ | ADCY9 | O60503 | 1/20 | 0.43 |
| ▸ | ADCY5 | O95622 | 1/20 | 0.43 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.43 |
| ▸ | GCGR | P47871 | 1/20 | 0.43 |
| ▸ | ADCY7 | P51828 | 1/20 | 0.43 |
| ▸ | ADCY2 | Q08462 | 1/20 | 0.43 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.43 |
| ▸ | ADCY4 | Q8NFM4 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7343580 | 0.87 | MCHR1 (0.42) | ALDH1A1MAPTTAAR1MCHR1MME | |
| SCHEMBL7306722 | 0.81 | NR1H4 (0.46) | ALDH1A1MAPTTAAR1KMT2AADRB1 | |
| SCHEMBL7348051 | 0.81 | ACP3 (0.50) | ALDH1A1MAPTMMEANPEP | |
| SCHEMBL7322719 | 0.81 | ACP3 (0.50) | ALDH1A1MAPTMMEANPEP | |
| SCHEMBL7315627 | 0.79 | ACP3 (0.43) | ALDH1A1MAPTKMT2AADRB1ADRB3 | |
| SCHEMBL7309958 | 0.79 | MMEL1 (0.58) | MME | |
| SCHEMBL7318079 | 0.79 | MMEL1 (0.58) | MME | |
| SCHEMBL7312117 | 0.77 | MME (0.52) | ALDH1A1KMT2AADRB1ADRB3NR1H4 | |
| SCHEMBL7312109 | 0.77 | MME (0.52) | ALDH1A1KMT2AADRB1ADRB3NR1H4 | |
| SCHEMBL7308004 | 0.75 | USP30 (0.54) | ALDH1A1TAAR1KMT2AADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0592367-A2 | Phosphono/biaryl substituted dipeptide derivatives | CIBA-GEIGY AG (CH) | 1994-04-13 | — | — | EP | disclosed |
| US-5294632-A | Diuretics and vasorelaxants | CIBA-GEIGY CORPORATION (US) | 1994-03-15 | — | — | US | disclosed |
| EP-0511940-A2 | Phosphono/biaryl substituted dipeptide derivatives | CIBA-GEIGY AG (CH) | 1992-11-04 | — | — | EP | disclosed |
| US-5155100-A | Treating cardiovascular disorders in mammals | CIBA-GEIGY CORPORATION (US) | 1992-10-13 | — | — | US | disclosed |