Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | KCNB1 | Q14721 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MME | P08473 | 1/20 | 0.39 |
| ▸ | ANPEP | P15144 | 1/20 | 0.39 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | F7 | P08709 | 1/20 | 0.37 |
| ▸ | F3 | P13726 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7308016 | 0.87 | ALDH1A1 (0.45) | MCHR1MAPTALDH1A1MMEANPEP | |
| SCHEMBL7343564 | 0.78 | USP30 (0.46) | MAPTTP53CYP1A2MMEANPEP | |
| SCHEMBL7348051 | 0.77 | ACP3 (0.50) | MAPTALDH1A1MMEANPEP | |
| SCHEMBL7322719 | 0.77 | ACP3 (0.50) | MAPTALDH1A1MMEANPEP | |
| SCHEMBL7309958 | 0.75 | MMEL1 (0.58) | MME | |
| SCHEMBL7318079 | 0.75 | MMEL1 (0.58) | MME | |
| SCHEMBL28291198 | 0.70 | TP53 (0.52) | MAPTTP53CYP1A2 | |
| SCHEMBL7308501 | 0.70 | MMEL1 (0.43) | — | |
| SCHEMBL7306722 | 0.69 | NR1H4 (0.46) | MAPTALDH1A1TAAR1 | |
| SCHEMBL7343009 | 0.68 | HDAC3 (0.39) | MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0592367-A2 | Phosphono/biaryl substituted dipeptide derivatives | CIBA-GEIGY AG (CH) | 1994-04-13 | — | — | EP | disclosed |