Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP3 | P15309 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.45 |
| ▸ | MME | P08473 | 5/20 | 0.45 |
| ▸ | ACE | P12821 | 4/20 | 0.45 |
| ▸ | CPA1 | P15085 | 2/20 | 0.45 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.45 |
| ▸ | ANPEP | P15144 | 1/20 | 0.45 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.43 |
| ▸ | PSAT1 | Q9Y617 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7348051 | 1.00 | ACP3 (0.50) | ACP3ALDH1A1MAPTADAMTS5MME | |
| SCHEMBL7309958 | 0.82 | MMEL1 (0.58) | MMEACE | |
| SCHEMBL7318079 | 0.82 | MMEL1 (0.58) | MMEACE | |
| SCHEMBL7411122 | 0.82 | ALDH1A1 (0.52) | ACP3ALDH1A1MAPTADAMTS5MME | |
| SCHEMBL7308016 | 0.81 | ALDH1A1 (0.45) | ALDH1A1MAPTMMEANPEP | |
| SCHEMBL10197473 | 0.79 | ALDH1A1 (0.68) | ALDH1A1MAPTADAMTS5MMEACE | |
| SCHEMBL7308501 | 0.77 | MMEL1 (0.43) | — | |
| SCHEMBL7343580 | 0.77 | MCHR1 (0.42) | ALDH1A1MAPTMMEANPEP | |
| SCHEMBL22872362 | 0.75 | ADAMTS5 (0.51) | ALDH1A1MAPTADAMTS5CPA1 | |
| SCHEMBL13957690 | 0.75 | ADAMTS5 (0.51) | ALDH1A1MAPTADAMTS5CPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0592367-A2 | Phosphono/biaryl substituted dipeptide derivatives | CIBA-GEIGY AG (CH) | 1994-04-13 | — | — | EP | disclosed |
| US-5294632-A | Diuretics and vasorelaxants | CIBA-GEIGY CORPORATION (US) | 1994-03-15 | — | — | US | disclosed |
| EP-0511940-A2 | Phosphono/biaryl substituted dipeptide derivatives | CIBA-GEIGY AG (CH) | 1992-11-04 | — | — | EP | disclosed |
| US-5155100-A | Treating cardiovascular disorders in mammals | CIBA-GEIGY CORPORATION (US) | 1992-10-13 | — | — | US | disclosed |