Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 3/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.48 |
| ▸ | P2RX7 | Q99572 | 6/20 | 0.45 |
| ▸ | CTSK | P43235 | 7/20 | 0.43 |
| ▸ | CTSB | P07858 | 6/20 | 0.43 |
| ▸ | CTSS | P25774 | 6/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | REN | P00797 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7308737 | 0.91 | P2RX7 (0.47) | ITGB3ITGA2BP2RX7CTSKCTSB | |
| SCHEMBL7307823 | 0.85 | P2RX7 (0.46) | P2RX7CTSKCTSBCTSSCTSL | |
| SCHEMBL7933465 | 0.84 | PREP (0.52) | ITGB3ITGA2BCTSKCTSBCTSS | |
| SCHEMBL7933461 | 0.84 | PREP (0.52) | ITGB3ITGA2BCTSKCTSBCTSS | |
| SCHEMBL7933471 | 0.84 | PREP (0.52) | ITGB3ITGA2BCTSKCTSBCTSS | |
| SCHEMBL7304992 | 0.83 | ITGB3 (0.65) | ITGB3ITGA2B | |
| SCHEMBL7371886 | 0.83 | P2RX7 (0.48) | P2RX7CTSKCTSL | |
| SCHEMBL7298331 | 0.83 | ITGB3 (0.46) | ITGB3ITGA2BP2RX7CTSKCTSS | |
| SCHEMBL7371887 | 0.83 | P2RX7 (0.48) | P2RX7CTSKCTSL | |
| SCHEMBL7371888 | 0.83 | P2RX7 (0.48) | P2RX7CTSKCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0643072-B1 | 2-Piperazinone compounds and their use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1999-02-24 | — | — | EP | disclosed |
| US-5550131-A | ANTITHROMBOTIC AGENT | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-08-27 | — | — | US | disclosed |
| EP-0643072-A1 | 2-Piperazinone compounds and their use | Takeda Chemical Industries, Ltd. (JP) | 1995-03-15 | — | — | EP | disclosed |