Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 2/20 | 0.52 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.48 |
| ▸ | CAPN1 | P07384 | 3/20 | 0.46 |
| ▸ | CTSB | P07858 | 2/20 | 0.42 |
| ▸ | CTSK | P43235 | 2/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CCR1 | P32246 | 2/20 | 0.41 |
| ▸ | CASP1 | P29466 | 2/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | CASP6 | P55212 | 1/20 | 0.41 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7933461 | 1.00 | PREP (0.52) | PREPITGB3ITGA2BCAPN1CTSB | |
| SCHEMBL7933471 | 1.00 | PREP (0.52) | PREPITGB3ITGA2BCAPN1CTSB | |
| SCHEMBL7308737 | 0.85 | P2RX7 (0.47) | ITGB3ITGA2BCTSBCTSKCTSS | |
| SCHEMBL7308051 | 0.84 | ITGB3 (0.48) | ITGB3ITGA2BCTSBCTSKCTSS | |
| SCHEMBL7363004 | 0.78 | KLK7 (0.47) | CTSBCTSKCTSSCTSLCASP1 | |
| SCHEMBL7363000 | 0.78 | KLK7 (0.47) | CTSBCTSKCTSSCTSLCASP1 | |
| SCHEMBL7367319 | 0.78 | KLK7 (0.47) | CTSBCTSKCTSSCTSLCASP1 | |
| SCHEMBL7367317 | 0.78 | KLK7 (0.47) | CTSBCTSKCTSSCTSLCASP1 | |
| SCHEMBL7363006 | 0.78 | KLK7 (0.47) | CTSBCTSKCTSSCTSLCASP1 | |
| SCHEMBL7307823 | 0.78 | P2RX7 (0.46) | CTSBCTSKCTSSCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242600-B1 | ANTIISCHEMIC AGENTS, ANTICOAGULANTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-06-05 | — | — | US | disclosed |