Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 6/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | PRKDC | P78527 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7315888 | 0.86 | TDP1 (0.38) | TDP1HPGDSCN9ABCHEACHE | |
| SCHEMBL10376743 | 0.85 | HPGD (0.47) | TDP1HPGDBCHEACHEMEN1 | |
| SCHEMBL7315237 | 0.80 | SIGMAR1 (0.39) | HPGDSCN9AMEN1KMT2ANPC1 | |
| SCHEMBL7308198 | 0.78 | ALDH1A1 (0.34) | KDM4EALDH1A1CYP3A4MAPTALOX15 | |
| SCHEMBL7317175 | 0.75 | ALDH1A1 (0.47) | TDP1HPGDKMT2ANPC1SMN1; SMN2 | |
| SCHEMBL7317136 | 0.74 | ALDH1A1 (0.45) | TDP1HPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10375971 | 0.74 | HPGD (0.44) | HPGDMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL7312076 | 0.74 | THRB (0.45) | HPGDBCHEACHEMEN1KMT2A | |
| SCHEMBL7319139 | 0.74 | ALDH1A1 (0.46) | TDP1HPGDMEN1KMT2ANPC1 | |
| Hydrochloric Acid SCHEMBL7319148 | 0.74 | ALDH1A1 (0.46) | TDP1HPGDKMT2ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |