Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 6/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 2/20 | 0.34 |
| ▸ | ACHE | P22303 | 2/20 | 0.34 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 2/20 | 0.32 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.32 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.32 |
| ▸ | THRA | P10827 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7308201 | 0.86 | TDP1 (0.39) | TDP1SCN9AMEN1KMT2AHPGD | |
| SCHEMBL7314747 | 0.80 | SIGMAR1 (0.38) | SCN9AMEN1KMT2AHPGDNPC1 | |
| SCHEMBL7315879 | 0.80 | SIRT3 (0.36) | SIRT3THRATHRB | |
| SCHEMBL7317566 | 0.74 | THRB (0.44) | KMT2AHPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10376743 | 0.73 | HPGD (0.47) | TDP1MEN1KMT2AHPGDNPC1 | |
| SCHEMBL7320170 | 0.68 | KMT2A (0.37) | MEN1KMT2AHPGDNPC1RAB9A | |
| SCHEMBL7310447 | 0.67 | PDE3B (0.55) | MEN1KMT2AHPGD | |
| SCHEMBL7308198 | 0.67 | ALDH1A1 (0.34) | THRATHRB | |
| SCHEMBL7319721 | 0.66 | PDE3B (0.56) | TDP1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL7315902 | 0.66 | HTR7 (0.34) | MEN1KMT2ASIRT3CYSLTR2CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |